The value of customized medicine has increased significantly in recent years, especially in the context of orally administered pharmaceuticals, where the important aspects are choosing the right dose of the active substance for a particular patient and delivering it to a target place. Through the implementation of additive manufacturing technologies, medications can be precisely tailored according to the required specifications. In addition, the use of appropriate materials enables the controlled release of the drug. Hydrogels are one of the materials under consideration for this kind of application, which are characterized by the ability to modify their properties in response to external stimuli. This feature was used in the controlled release of the active substance from a hydrogel drug delivery system in a simulated gastrointestinal tract in in vitro tests. This work presents results on the mechanical characteristics and controlled release of active substance from a hydrogel drug delivery system fabricated using additive manufacturing technology.