Optimizing Synthesis Parameters for Near-Infrared Emitting Ag₂S Quantum Dots


"Enhancing the synthesis of quantum dots holds paramount significance as it allows for precise modulation of their spectroscopic attributes through meticulous adjustment of reaction parameters such as temperature, duration, pH, capping agent, and reagent concentration. Among these, silver sulfide quantum dots (Ag2S QDs) stand out for their immense potential in theranostics owing to a combination of favorable traits: minimal toxicity, heightened quantum yield, robust photostability, biocompatibility, and emission falling within the near-infrared (NIR) spectrum, facilitating advanced imaging capabilities. While traditional organic fluorescent dyes boast commendable optical characteristics, they grapple with a multitude of challenges, notably the vexing issue of autofluorescence stemming from inherent fluorophores within biological systems. Enterprising advancements in silver sulfide quantum dots, particularly those emitting in the NIR II window (1000-1400 nm), present a promising avenue for addressing these hurdles. Their emission properties, extending into the second NIR window, afford unparalleled advantages, including reduced light scattering and negligible autofluorescence, thereby enabling deep-penetration imaging with unprecedented clarity and precision. Within this study, we unveil a refined synthesis methodology for Ag2S QDs, fortified with an innovative stabilizing shell. Moreover, our endeavors delve into the comprehensive characterization of these QDs, elucidating their emission and excitation spectra, alongside delving into the intricacies of their lifetime dynamics."

2nd International Conference on Advanced Materials for Bio-Related Applications